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ICD-10-CM 2027 diagnosis code

E24.2Drug-induced Cushing's syndrome

✓ Billable / specificCC — complication/comorbidity

E24.2 is a valid, billable ICD-10-CM code for drug-induced cushing's syndrome. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Looking up by condition? See ICD-10 code for Hypercortisonism, ICD-10 code for Hypercorticosteronism, ICD-10 code for Cushingoid due to steroid therapy.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E24.2

E24.2 is the ICD-10-CM diagnosis code for drug-induced Cushing's syndrome. It belongs to category E24 (Cushing's syndrome), block E20-E35 (disorders of other endocrine glands) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E24 (Cushing's syndrome), E24.2 is specifically for drug-induced Cushing's syndrome. Related codes cover Pituitary-dependent Cushing's disease (E24.0), Nelson's syndrome (E24.1), ectopic ACTH syndrome (E24.3), alcohol-induced pseudo-Cushing's syndrome (E24.4), other Cushing's syndrome (E24.8) and unspecified (E24.9).

Use an additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 255.0 (Cushing's syndrome).

Coding notes

Use additional codeAdd a secondary code to fully describe the condition
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Notes that apply from higher levels

Instructions written at a parent level also apply to E24.2.

› From E24 Cushing's syndrome
Excludes1
  • congenital adrenal hyperplasia (E25.0)

Broader instructions also apply from E20-E35 Disorders of other endocrine glands and Chapter 4: Endocrine, nutritional and metabolic diseases.

Alphabetic index entries

9 entries

Terms in the official ICD-10-CM index that lead to E24.2.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 255.0Cushing's syndromeapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E24.2

Is E24.2 billable?

Yes. E24.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E24.2 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E24.2 as a principal diagnosis.

Is E24.2 a CC or MCC?

E24.2 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does E24.2 group to?

E24.2 is used in the MS-DRG v44.0 logic for MS-DRG 643 (Endocrine Disorders with MCC), MS-DRG 644 (Endocrine Disorders with CC) and MS-DRG 645 (Endocrine Disorders without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for E24.2?

The CMS General Equivalence Mappings map E24.2 to ICD-9-CM 255.0.