ICD-10-CM 2027
ICD-10 code for elevated transaminases
Confirmed by the official ICD-10-CM index entry “elevated, elevation › transaminase level”. Page updated September 29, 2026.
About coding elevated transaminases
The ICD-10-CM code for elevated transaminases is R74.01 (Elevation of levels of liver transaminase levels). The official index lists 2 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on R74.01.
It is also searched as elevated ALT, elevated AST, transaminitis.
Within R74.0 (nonspecific elevation of levels of transaminase and lactic acid dehydrogenase [LDH]), R74.01 is specifically for elevation of levels of liver transaminase levels. Related codes cover lactic acid dehydrogenase [LDH] (R74.02).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 947 (Signs and Symptoms with MCC, relative weight 1.261) and DRG 948 (Signs and Symptoms without MCC, relative weight 0.7835), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Related Elevated transaminases codes
Common questions about elevated transaminases ICD-10 codes
What is the ICD-10 code for elevated transaminases?
- R74.01 — Elevation of levels of liver transaminase levels. More specific codes apply when the documentation supports them: R74.02, R74.8.
What is the ICD-10 code for elevation of levels of lactic acid dehydrogenase [ldh]?
- R74.02 — Elevation of levels of lactic acid dehydrogenase [LDH].
What is the ICD-10 code for abnormal levels of other serum enzymes?
- R74.8 — Abnormal levels of other serum enzymes.
Is R74.01 billable?
- Yes. R74.01 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R74.01 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R74.01 as a principal diagnosis.
Is R74.01 a CC or MCC?
- No. R74.01 is neither a CC nor an MCC under MS-DRG v44.0.