ICD-10-CM 2027 diagnosis code
R74.01Elevation of levels of liver transaminase levels
R74.01 is a valid, billable ICD-10-CM code for elevation of levels of liver transaminase levels. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Looking up by condition? See ICD-10 code for Elevated transaminases, ICD-10 code for Transaminasemia.
Code last changed in FY2021 (effective October 1, 2020). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About R74.01
R74.01 is the ICD-10-CM diagnosis code for elevation of levels of liver transaminase levels. It belongs to category R74 (abnormal serum enzyme levels), block R70-R79 (abnormal findings on examination of blood, without diagnosis) and chapter 18 (symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within R74.0 (nonspecific elevation of levels of transaminase and lactic acid dehydrogenase [LDH]), R74.01 is specifically for elevation of levels of liver transaminase levels. Related codes cover lactic acid dehydrogenase [LDH] (R74.02).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 947 (Signs and Symptoms with MCC, relative weight 1.261) and DRG 948 (Signs and Symptoms without MCC, relative weight 0.7835), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It was added in FY2021, effective October 1, 2020.
Coding notes
- Elevation of levels of alanine transaminase (ALT)
- Elevation of levels of aspartate transaminase (AST)
Notes that apply from higher levels
Instructions written at a parent level also apply to R74.01.
Broader instructions also apply from R70-R79 Abnormal findings on examination of blood, without diagnosis and Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.
Alphabetic index entries
12 entriesTerms in the official ICD-10-CM index that lead to R74.01.
- Elevated, elevation › alanine transaminase (ALT)
- Elevated, elevation › ALT (alanine transaminase)
- Elevated, elevation › aspartate transaminase (AST)
- Elevated, elevation › AST (aspartate transaminase)
- Elevated, elevation › liver function › test › aminotransferase
- Elevated, elevation › SGOT
- Elevated, elevation › SGPT
- Elevated, elevation › transaminase level
- Findings, abnormal, inconclusive, without diagnosis › SGOT
- Findings, abnormal, inconclusive, without diagnosis › SGPT
- Findings, abnormal, inconclusive, without diagnosis › transaminase (level)
- Transaminasemia
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 23 · Factors Influencing Health Status and Other Contacts with Health Services
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2021 (effective 10/1/2020): Added
- No changes since FY2021.
Common questions about R74.01
Is R74.01 billable?
- Yes. R74.01 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R74.01 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R74.01 as a principal diagnosis.
Is R74.01 a CC or MCC?
- No. R74.01 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does R74.01 group to?
- R74.01 is used in the MS-DRG v44.0 logic for MS-DRG 947 (Signs and Symptoms with MCC) and MS-DRG 948 (Signs and Symptoms without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.