ICD-10-CM 2027
ICD-10 code for Encephalopathia hyperbilirubinemica
From the official ICD-10-CM alphabetic index entry “Encephalopathia hyperbilirubinemica, newborn”. Page updated September 29, 2026.
About coding Encephalopathia hyperbilirubinemica
The ICD-10-CM code for Encephalopathia hyperbilirubinemica is P57.9 (Kernicterus, unspecified). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on P57.9.
Within P57, choose P57.9 (unspecified) only when documentation doesn't support a more specific option: due to isoimmunization (P57.0) and other specified kernicterus (P57.8).
As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 791 (Prematurity with Major Problems, relative weight 4.1075) and DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Encephalopathia hyperbilirubinemica codes (official index)
- due to isoimmunization (conditions in P55) P57.0 — Kernicterus due to isoimmunization
Common questions about Encephalopathia hyperbilirubinemica ICD-10 codes
What is the ICD-10 code for Encephalopathia hyperbilirubinemica?
- P57.9 — Kernicterus, unspecified. More specific codes apply when the documentation supports them: P57.0.
Is P57.9 billable?
- Yes. P57.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can P57.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict P57.9 as a principal diagnosis.
Is P57.9 a CC or MCC?
- P57.9 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.