ICD-10-CM 2027
ICD-10 code for fructose metabolism disturbance
From the official ICD-10-CM alphabetic index entry “Disturbance (s) › fructose metabolism”. Page updated September 29, 2026.
About coding fructose metabolism disturbance
The ICD-10-CM code for fructose metabolism disturbance is E74.10 (Disorder of fructose metabolism, unspecified).
Within E74.1, choose E74.10 (Disorder of fructose metabolism, unspecified) only when documentation doesn't support a more specific option: essential fructosuria (E74.11), hereditary fructose intolerance (E74.12) and other disorders of fructose metabolism (E74.19).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 391 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders with MCC, relative weight 1.2392) and DRG 392 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders without MCC, relative weight 0.7645), in MDC 06 (Diseases and Disorders of the Digestive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about fructose metabolism disturbance ICD-10 codes
What is the ICD-10 code for fructose metabolism disturbance?
- E74.10 — Disorder of fructose metabolism, unspecified.
Is E74.10 billable?
- Yes. E74.10 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E74.10 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E74.10 as a principal diagnosis.
Is E74.10 a CC or MCC?
- No. E74.10 is neither a CC nor an MCC under MS-DRG v44.0.