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ICD-10-CM 2027

ICD-10 code for hemoglobin disease abnormal

D58.2

Other hemoglobinopathies

✓ Billable / specific

From the official ICD-10-CM alphabetic index entry “Abnormal, abnormality, abnormalities › hemoglobin (disease)”. Page updated September 29, 2026.

About coding hemoglobin disease abnormal

The ICD-10-CM code for hemoglobin disease abnormal is D58.2 (Other hemoglobinopathies).

Within D58, choose D58.2 (Other hemoglobinopathies) only when documentation doesn't support a more specific option: hereditary spherocytosis (D58.0), hereditary elliptocytosis (D58.1), other specified hereditary hemolytic anemias (D58.8) and hereditary hemolytic anemia, unspecified (D58.9).

Don't report D58.2 together with the conditions in its Excludes1 note: familial polycythemia (D75.0), Hb-M disease (D74.0), hemoglobin E-beta thalassemia (D56.5), hereditary persistence of fetal hemoglobin [HPFH] (D56.4) and 3 more.

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

More specific hemoglobin disease abnormal codes (official index)

  • trait

Don't confuse with (Excludes1 for D58.2)

  • familial polycythemia (D75.0)
  • Hb-M disease (D74.0)
  • hemoglobin E-beta thalassemia (D56.5)
  • hereditary persistence of fetal hemoglobin [HPFH] (D56.4)
  • high-altitude polycythemia (D75.1)
  • methemoglobinemia (D74.-)
  • other hemoglobinopathies with thalassemia (D56.8)

Common questions about hemoglobin disease abnormal ICD-10 codes

What is the ICD-10 code for hemoglobin disease abnormal?

D58.2 — Other hemoglobinopathies.

Is D58.2 billable?

Yes. D58.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D58.2 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict D58.2 as a principal diagnosis.

Is D58.2 a CC or MCC?

No. D58.2 is neither a CC nor an MCC under MS-DRG v44.0.