ICD-10-CM 2027 diagnosis code
D58.2Other hemoglobinopathies
D58.2 is a valid, billable ICD-10-CM code for other hemoglobinopathies. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Looking up by condition? See ICD-10 code for Hemoglobinopathy, ICD-10 code for Heinz body anemia, ICD-10 code for Constant Spring hemoglobin, ICD-10 code for Hemoglobin disease abnormal.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About D58.2
D58.2 is the ICD-10-CM diagnosis code for other hemoglobinopathies. It belongs to category D58 (other hereditary hemolytic anemias), block D55-D59 (hemolytic anemias) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within D58, choose D58.2 (Other hemoglobinopathies) only when documentation doesn't support a more specific option: hereditary spherocytosis (D58.0), hereditary elliptocytosis (D58.1), other specified hereditary hemolytic anemias (D58.8) and hereditary hemolytic anemia, unspecified (D58.9).
Don't report D58.2 together with the conditions in its Excludes1 note: familial polycythemia (D75.0), Hb-M disease (D74.0), hemoglobin E-beta thalassemia (D56.5), hereditary persistence of fetal hemoglobin [HPFH] (D56.4) and 3 more.
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 811 (Red Blood Cell Disorders with MCC, relative weight 1.3988) and DRG 812 (Red Blood Cell Disorders without MCC, relative weight 0.9234), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as 282.7 (other hemoglobinopathies).
Coding notes
- Abnormal hemoglobin NOS
- Congenital Heinz body anemia
- Hb-C disease
- Hb-D disease
- Hb-E disease
- Hemoglobinopathy NOS
- Unstable hemoglobin hemolytic disease
Notes that apply from higher levels
Instructions written at a parent level also apply to D58.2.
› From D58 Other hereditary hemolytic anemias
- hemolytic anemia of the newborn (P55.-)
Broader instructions also apply from Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.
Alphabetic index entries
40 entriesTerms in the official ICD-10-CM index that lead to D58.2.
- Abnormal, abnormality, abnormalities › hemoglobin (disease)
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › congenital › Heinz body
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › Heinz body, congenital
- Arthritis, arthritic (acute) (chronic) (nonpyogenic) (subacute) › in (due to) › hemoglobinopathy NEC
- Arthropathy › in (due to) › hemoglobinopathy NEC
- Disease, diseased › hemoglobin or Hb › abnormal (mixed) NEC
- Disease, diseased › hemoglobin or Hb › C (Hb-C)
- Disease, diseased › hemoglobin or Hb › C (Hb-C) › with other abnormal hemoglobin NEC
- Disease, diseased › hemoglobin or Hb › Constant Spring
- Disease, diseased › hemoglobin or Hb › D (Hb-D)
- Disease, diseased › hemoglobin or Hb › E (Hb-E)
- Disease, diseased › hemoglobin or Hb › unstable, hemolytic
- Disease, diseased › hemolytic (newborn) › unstable hemoglobin
- Heinz body anemia, congenital
- Hemoglobin › Constant Spring
- Hemoglobinopathy (mixed)
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › carpus
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › clavicle
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › femur
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › fibula
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › finger
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › humerus
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › ilium
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › ischium
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › metacarpus
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › metatarsus
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › multiple sites
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › neck
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › radius
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › rib
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › scapula
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › skull
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › specified NEC
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › tarsus
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › tibia
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › toe
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › ulna
- Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › vertebra
- Trait (s) › hemoglobin › abnormal NEC
Codes whose notes reference D58.2
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 16 · Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders
ICD-9-CM equivalent
Converter →- 282.7Other hemoglobinopathiesapproximate
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about D58.2
Is D58.2 billable?
- Yes. D58.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D58.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D58.2 as a principal diagnosis.
Is D58.2 a CC or MCC?
- No. D58.2 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does D58.2 group to?
- D58.2 is used in the MS-DRG v44.0 logic for MS-DRG 811 (Red Blood Cell Disorders with MCC) and MS-DRG 812 (Red Blood Cell Disorders without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for D58.2?
- The CMS General Equivalence Mappings map D58.2 to ICD-9-CM 282.7.