ICD-10-CM 2027
ICD-10 code for hemoglobin disease spherocytosis
From the official ICD-10-CM alphabetic index entry “Spherocytosis (congenital) (familial) (hereditary) › hemoglobin disease”. Page updated September 29, 2026.
About coding hemoglobin disease spherocytosis
The ICD-10-CM code for hemoglobin disease spherocytosis is D58.0 (Hereditary spherocytosis).
Within D58 (other hereditary hemolytic anemias), D58.0 is specifically for hereditary spherocytosis. Related codes cover hereditary elliptocytosis (D58.1), other hemoglobinopathies (D58.2), other specified hereditary hemolytic anemias (D58.8) and hereditary hemolytic anemia, unspecified (D58.9).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 811 (Red Blood Cell Disorders with MCC, relative weight 1.3988) and DRG 812 (Red Blood Cell Disorders without MCC, relative weight 0.9234), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about hemoglobin disease spherocytosis ICD-10 codes
What is the ICD-10 code for hemoglobin disease spherocytosis?
- D58.0 — Hereditary spherocytosis.
Is D58.0 billable?
- Yes. D58.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D58.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D58.0 as a principal diagnosis.
Is D58.0 a CC or MCC?
- No. D58.0 is neither a CC nor an MCC under MS-DRG v44.0.