ICD-10-CM 2027
ICD-10 code for Hexokinase deficiency anemia
From the official ICD-10-CM alphabetic index entry “Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › hexokinase deficiency”. Page updated September 29, 2026.
About coding Hexokinase deficiency anemia
The ICD-10-CM code for Hexokinase deficiency anemia is D55.29 (Anemia due to other disorders of glycolytic enzymes).
Within D55.2, choose D55.29 (other disorders of glycolytic enzymes) only when documentation doesn't support a more specific option: pyruvate kinase deficiency (D55.21).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 811 (Red Blood Cell Disorders with MCC, relative weight 1.3988) and DRG 812 (Red Blood Cell Disorders without MCC, relative weight 0.9234), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Hexokinase deficiency anemia ICD-10 codes
What is the ICD-10 code for Hexokinase deficiency anemia?
- D55.29 — Anemia due to other disorders of glycolytic enzymes.
Is D55.29 billable?
- Yes. D55.29 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D55.29 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D55.29 as a principal diagnosis.
Is D55.29 a CC or MCC?
- No. D55.29 is neither a CC nor an MCC under MS-DRG v44.0.