ICD-10-CM 2027
ICD-10 code for Hyperadrenocorticism
From the official ICD-10-CM alphabetic index entry “Hyperadrenocorticism”. Page updated September 29, 2026.
About coding Hyperadrenocorticism
The ICD-10-CM code for Hyperadrenocorticism is E24.9 (Cushing's syndrome, unspecified). The official index lists 4 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E24.9.
Within E24, choose E24.9 (unspecified) only when documentation doesn't support a more specific option: Pituitary-dependent Cushing's disease (E24.0), Nelson's syndrome (E24.1), drug-induced Cushing's syndrome (E24.2), ectopic ACTH syndrome (E24.3), alcohol-induced pseudo-Cushing's syndrome (E24.4) and other Cushing's syndrome (E24.8).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Hyperadrenocorticism codes (official index)
- congenital E25.0 — Congenital adrenogenital disorders associated with enzyme deficiency
- iatrogenic E24.2 — Drug-induced Cushing's syndrome
- correct substance properly administered
- overdose or wrong substance given or taken
- not associated with Cushing's syndrome E27.0 — Other adrenocortical overactivity
- pituitary-dependent E24.0 — Pituitary-dependent Cushing's disease
Common questions about Hyperadrenocorticism ICD-10 codes
What is the ICD-10 code for Hyperadrenocorticism?
- E24.9 — Cushing's syndrome, unspecified. More specific codes apply when the documentation supports them: E25.0, E24.2, E27.0, E24.0.
What is the ICD-10 code for congenital hyperadrenocorticism?
- E25.0 — Congenital adrenogenital disorders associated with enzyme deficiency.
What is the ICD-10 code for iatrogenic hyperadrenocorticism?
- E24.2 — Drug-induced Cushing's syndrome.
What is the ICD-10 code for pituitary-dependent hyperadrenocorticism?
- E24.0 — Pituitary-dependent Cushing's disease.
Is E24.9 billable?
- Yes. E24.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E24.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E24.9 as a principal diagnosis.
Is E24.9 a CC or MCC?
- E24.9 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.