ICD-10-CM 2027
ICD-10 code for hypoxic ischemic encephalopathy
Hypoxic ischemic encephalopathy [HIE], unspecified
From the official ICD-10-CM alphabetic index entry “Encephalopathy (acute) › hypoxic ischemic”. Page updated September 29, 2026.
About coding hypoxic ischemic encephalopathy
The ICD-10-CM code for hypoxic ischemic encephalopathy is P91.60 (Hypoxic ischemic encephalopathy [HIE], unspecified). The official index lists 3 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on P91.60.
Within P91.6, choose P91.60 (unspecified) only when documentation doesn't support a more specific option: mild hypoxic ischemic encephalopathy [HIE] (P91.61), moderate hypoxic ischemic encephalopathy [HIE] (P91.62) and severe hypoxic ischemic encephalopathy [HIE] (P91.63).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 794 (Neonate with Other Significant Problems, relative weight 1.4935), in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific hypoxic ischemic encephalopathy codes (official index)
Common questions about hypoxic ischemic encephalopathy ICD-10 codes
What is the ICD-10 code for hypoxic ischemic encephalopathy?
- P91.60 — Hypoxic ischemic encephalopathy [HIE], unspecified. More specific codes apply when the documentation supports them: P91.61, P91.62, P91.63.
What is the ICD-10 code for mild hypoxic ischemic encephalopathy?
- P91.61 — Mild hypoxic ischemic encephalopathy [HIE].
What is the ICD-10 code for moderate hypoxic ischemic encephalopathy?
- P91.62 — Moderate hypoxic ischemic encephalopathy [HIE].
What is the ICD-10 code for severe hypoxic ischemic encephalopathy?
- P91.63 — Severe hypoxic ischemic encephalopathy [HIE].
Is P91.60 billable?
- Yes. P91.60 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can P91.60 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict P91.60 as a principal diagnosis.
Is P91.60 a CC or MCC?
- P91.60 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.