ICD-10-CM 2027 diagnosis code
P91.6Hypoxic ischemic encephalopathy [HIE]
P91.6 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About P91.6
P91.6 is the ICD-10-CM diagnosis code for hypoxic ischemic encephalopathy [HIE]. It belongs to category P91 (other disturbances of cerebral status of newborn), block P90-P96 (other disorders originating in the perinatal period) and chapter 16 (certain conditions originating in the perinatal period). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.
Within P91 (other disturbances of cerebral status of newborn), P91.6 is specifically for hypoxic ischemic encephalopathy [HIE]. Related codes cover neonatal cerebral ischemia (P91.0), acquired periventricular cysts of newborn (P91.1), neonatal cerebral leukomalacia (P91.2), neonatal cerebral irritability (P91.3), neonatal cerebral depression (P91.4), neonatal coma (P91.5), other specified disturbances of cerebral status of newborn (P91.8) and disturbance of cerebral status of newborn, unspecified (P91.9).
To report this condition, pick the subcode that matches the documentation: P91.60 (unspecified), P91.61 ([HIE]), P91.62 ([HIE]) and P91.63 ([HIE]).
Don't report P91.6 together with the conditions in its Excludes1 note: Neonatal cerebral depression (P91.4), Neonatal cerebral irritability (P91.3) and Neonatal coma (P91.5).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under P91.6
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to P91.6.
Broader instructions also apply from Chapter 16: Certain conditions originating in the perinatal period.
Codes whose notes reference P91.6
- P84Excludes1
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about P91.6
Is P91.6 billable?
- No. P91.6 is a header code. Report one of its more specific subcodes instead.