ICD-10-CM 2027
ICD-10 code for insulin long-term drug therapy
From the official ICD-10-CM alphabetic index entry “Long-term (current) (prophylactic) drug therapy (use of) › insulin”. Page updated September 29, 2026.
About coding insulin long-term drug therapy
The ICD-10-CM code for insulin long-term drug therapy is Z79.4 (Long term (current) use of insulin).
Within Z79 (long term (current) drug therapy), Z79.4 is specifically for long term (current) use of insulin. Related codes cover long term (current) use of anticoagulants and antithrombotics/antiplatelets (Z79.0), long term (current) use of non-steroidal anti-inflammatories (NSAID) (Z79.1), long term (current) use of antibiotics (Z79.2), long term (current) use of hormonal contraceptives (Z79.3), long term (current) use of steroids (Z79.5), long term (current) use of immunomodulators and immunosuppressants (Z79.6) and other long term (current) drug therapy (Z79.8).
The conditions in its Excludes2 note aren't part of Z79.4, but may be coded alongside it if the patient has both: long-term (current) use of injectable non-insulin antidiabetic drugs (Z79.85), long term (current) use of oral antidiabetic drugs (Z79.84) and long term (current) use of oral hypoglycemic drugs (Z79.84).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Common questions about insulin long-term drug therapy ICD-10 codes
What is the ICD-10 code for insulin long-term drug therapy?
- Z79.4 — Long term (current) use of insulin.
Is Z79.4 billable?
- Yes. Z79.4 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Z79.4 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict Z79.4 as a principal diagnosis.
Is Z79.4 a CC or MCC?
- No. Z79.4 is neither a CC nor an MCC under MS-DRG v44.0.