ICD-10-CM 2027
ICD-10 code for IRDS syndrome
Respiratory distress syndrome of newborn
From the official ICD-10-CM alphabetic index entry “Syndrome › IRDS (idiopathic respiratory distress, newborn)”. Page updated September 29, 2026.
About coding IRDS syndrome
The ICD-10-CM code for IRDS syndrome is P22.0 (Respiratory distress syndrome of newborn).
Within P22 (respiratory distress of newborn), P22.0 is specifically for respiratory distress syndrome of newborn. Related codes cover transient tachypnea of newborn (P22.1), other respiratory distress of newborn (P22.8) and unspecified (P22.9).
The conditions in its Excludes2 note aren't part of P22.0, but may be coded alongside it if the patient has both: respiratory arrest of newborn (P28.81) and respiratory failure of newborn NOS (P28.5).
As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.
Common questions about IRDS syndrome ICD-10 codes
What is the ICD-10 code for IRDS syndrome?
- P22.0 — Respiratory distress syndrome of newborn.
Is P22.0 billable?
- Yes. P22.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can P22.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict P22.0 as a principal diagnosis.
Is P22.0 a CC or MCC?
- P22.0 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.