ICD-10-CM 2027
ICD-10 code for Leukocytopenia
From the official ICD-10-CM alphabetic index entry “Leukocytopenia”. Page updated September 29, 2026.
About coding Leukocytopenia
The ICD-10-CM code for Leukocytopenia is D72.819 (Decreased white blood cell count, unspecified).
Within D72.81, choose D72.819 (unspecified) only when documentation doesn't support a more specific option: Lymphocytopenia (D72.810) and other decreased white blood cell count (D72.818).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 814 (Reticuloendothelial and Immunity Disorders with MCC, relative weight 2.0729), DRG 815 (Reticuloendothelial and Immunity Disorders with CC, relative weight 1.0444) and DRG 816 (Reticuloendothelial and Immunity Disorders without CC/MCC, relative weight 0.7381), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Leukocytopenia ICD-10 codes
What is the ICD-10 code for Leukocytopenia?
- D72.819 — Decreased white blood cell count, unspecified.
Is D72.819 billable?
- Yes. D72.819 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D72.819 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D72.819 as a principal diagnosis.
Is D72.819 a CC or MCC?
- No. D72.819 is neither a CC nor an MCC under MS-DRG v44.0.