D72.81Decreased white blood cell count

D72.81 is the ICD-10-CM diagnosis code for decreased white blood cell count. It belongs to category D72 (other disorders of white blood cells), block D70-D77 (other disorders of blood and blood-forming organs) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within D72.8 (other specified disorders of white blood cells), D72.81 is specifically for decreased white blood cell count. Related codes cover elevated white blood cell count (D72.82) and other specified disorders of white blood cells (D72.89).

To report this condition, pick the subcode that matches the documentation: D72.810 (Lymphocytopenia), D72.818 (count) and D72.819 (unspecified).

The conditions in its Excludes2 note aren't part of D72.81, but may be coded alongside it if the patient has both: neutropenia (D70).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.