ICD-10-CM 2027
ICD-10 code for major depression
From the official ICD-10-CM alphabetic index entry “Depression (acute) (mental) › major”. Page updated September 29, 2026.
About coding major depression
The ICD-10-CM code for major depression is F32.9 (Major depressive disorder, single episode, unspecified). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on F32.9.
Within F32, choose F32.9 (Major depressive disorder, single episode, unspecified) only when documentation doesn't support a more specific option: major depressive disorder, single episode, mild (F32.0), major depressive disorder, single episode, moderate (F32.1), major depressive disorder, single episode, severe without psychotic features (F32.2), major depressive disorder, single episode, severe with psychotic features (F32.3), major depressive disorder, single episode, in partial remission (F32.4), major depressive disorder, single episode, in full remission (F32.5), other depressive episodes (F32.8) and depression, unspecified (F32.A).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 881 (Depressive Neuroses, relative weight 0.895), in MDC 19 (Mental Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific major depression codes (official index)
- with psychotic symptoms F32.3 — Major depressive disorder, single episode, severe with psychotic features
- recurrent
Common questions about major depression ICD-10 codes
What is the ICD-10 code for major depression?
- F32.9 — Major depressive disorder, single episode, unspecified. More specific codes apply when the documentation supports them: F32.3.
Is F32.9 billable?
- Yes. F32.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can F32.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict F32.9 as a principal diagnosis.
Is F32.9 a CC or MCC?
- No. F32.9 is neither a CC nor an MCC under MS-DRG v44.0.