ICD-10-CM 2027
ICD-10 code for motor neuron disease
From the official ICD-10-CM alphabetic index entry “Disease, diseased › motor neuron (bulbar) (mixed type) (spinal)”. Page updated September 29, 2026.
About coding motor neuron disease
The ICD-10-CM code for motor neuron disease is G12.20 (Motor neuron disease, unspecified). The official index lists 4 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on G12.20.
Within G12.2, choose G12.20 (unspecified) only when documentation doesn't support a more specific option: Amyotrophic lateral sclerosis (G12.21), progressive bulbar palsy (G12.22), primary lateral sclerosis (G12.23), familial motor neuron disease (G12.24), progressive spinal muscle atrophy (G12.25) and other motor neuron disease (G12.29).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 056 (Degenerative Nervous System Disorders with MCC, relative weight 2.2655) and DRG 057 (Degenerative Nervous System Disorders without MCC, relative weight 1.2838), in MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific motor neuron disease codes (official index)
Common questions about motor neuron disease ICD-10 codes
What is the ICD-10 code for motor neuron disease?
- G12.20 — Motor neuron disease, unspecified. More specific codes apply when the documentation supports them: G12.21, G12.24, G12.22, G12.29.
What is the ICD-10 code for amyotrophic lateral sclerosis motor neuron disease?
- G12.21 — Amyotrophic lateral sclerosis.
What is the ICD-10 code for familial motor neuron disease?
- G12.24 — Familial motor neuron disease.
What is the ICD-10 code for progressive bulbar palsy motor neuron disease?
- G12.22 — Progressive bulbar palsy.
Is G12.20 billable?
- Yes. G12.20 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can G12.20 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict G12.20 as a principal diagnosis.
Is G12.20 a CC or MCC?
- G12.20 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.