ICD-10-CM 2027
ICD-10 code for multinodular goiter
From the official ICD-10-CM alphabetic index entry “Goiter (plunging) (substernal) › multinodular (cystic) (nontoxic)”. Page updated September 29, 2026.
About coding multinodular goiter
The ICD-10-CM code for multinodular goiter is E04.2 (Nontoxic multinodular goiter). The official index lists 2 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E04.2.
Within E04 (other nontoxic goiter), E04.2 is specifically for nontoxic multinodular goiter. Related codes cover nontoxic diffuse goiter (E04.0), nontoxic single thyroid nodule (E04.1), other specified nontoxic goiter (E04.8) and nontoxic goiter, unspecified (E04.9).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific multinodular goiter codes (official index)
Common questions about multinodular goiter ICD-10 codes
What is the ICD-10 code for multinodular goiter?
- E04.2 — Nontoxic multinodular goiter. More specific codes apply when the documentation supports them: E05.20, E05.21.
What is the ICD-10 code for toxic or with hyperthyroidism multinodular goiter?
- E05.20 — Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm.
Is E04.2 billable?
- Yes. E04.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E04.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E04.2 as a principal diagnosis.
Is E04.2 a CC or MCC?
- No. E04.2 is neither a CC nor an MCC under MS-DRG v44.0.