ICD-10-CM 2027
ICD-10 code for necrolysis
From the official ICD-10-CM alphabetic index entry “Necrolysis, toxic epidermal”. Page updated September 29, 2026.
About coding necrolysis
The ICD-10-CM code for necrolysis is L51.2 (Toxic epidermal necrolysis [Lyell]).
Within L51 (erythema multiforme), L51.2 is specifically for toxic epidermal necrolysis [Lyell]. Related codes cover Nonbullous erythema multiforme (L51.0), Stevens-Johnson syndrome (L51.1), Stevens-Johnson syndrome-toxic epidermal necrolysis overlap syndrome (L51.3), other erythema multiforme (L51.8) and unspecified (L51.9).
Use an additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5). Use an additional code to identify associated manifestations, such as: arthropathy associated with dermatological disorders (M14.8-), conjunctival edema (H11.42), conjunctivitis (H10.22-), corneal scars and opacities (H17.-), corneal ulcer (H16.0-) and 7 more.
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
More specific necrolysis codes (official index)
- due to drug
- correct substance properly administered
- overdose or wrong substance given or taken
Common questions about necrolysis ICD-10 codes
What is the ICD-10 code for necrolysis?
- L51.2 — Toxic epidermal necrolysis [Lyell].
Is L51.2 billable?
- Yes. L51.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can L51.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict L51.2 as a principal diagnosis.
Is L51.2 a CC or MCC?
- L51.2 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.