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ICD-10-CM 2027 diagnosis code

L51.2Toxic epidermal necrolysis [Lyell]

✓ Billable / specificCC — complication/comorbidity

L51.2 is a valid, billable ICD-10-CM code for toxic epidermal necrolysis [lyell]. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Looking up by condition? See ICD-10 code for Necrolysis, ICD-10 code for Lyell's syndrome.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About L51.2

L51.2 is the ICD-10-CM diagnosis code for toxic epidermal necrolysis [Lyell]. It belongs to category L51 (erythema multiforme), block L49-L54 (urticaria and erythema) and chapter 12 (diseases of the skin and subcutaneous tissue). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within L51 (erythema multiforme), L51.2 is specifically for toxic epidermal necrolysis [Lyell]. Related codes cover Nonbullous erythema multiforme (L51.0), Stevens-Johnson syndrome (L51.1), Stevens-Johnson syndrome-toxic epidermal necrolysis overlap syndrome (L51.3), other erythema multiforme (L51.8) and unspecified (L51.9).

Use an additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5). Use an additional code to identify associated manifestations, such as: arthropathy associated with dermatological disorders (M14.8-), conjunctival edema (H11.42), conjunctivitis (H10.22-), corneal scars and opacities (H17.-), corneal ulcer (H16.0-) and 7 more.

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 595 (Major Skin Disorders with MCC, relative weight 2.0239) and DRG 596 (Major Skin Disorders without MCC, relative weight 1.1071), in MDC 09 (Diseases and Disorders of the Skin, Subcutaneous Tissue and Breast), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 695.15 (toxic epidermal necrolysis).

Notes that apply from higher levels

Instructions written at a parent level also apply to L51.2.

› From L51 Erythema multiforme
Excludes1
  • staphylococcal scalded skin syndrome (L00)
  • Ritter's disease (L00)
Use additional code
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • code to identify associated manifestations, such as:
  • arthropathy associated with dermatological disorders (M14.8-)
  • conjunctival edema (H11.42)
  • conjunctivitis (H10.22-)
  • corneal scars and opacities (H17.-)
  • corneal ulcer (H16.0-)
  • edema of eyelid (H02.84-)
  • inflammation of eyelid (H01.8-)
  • keratoconjunctivitis sicca (H16.22-)
  • mechanical lagophthalmos (H02.22-)
  • stomatitis (K12.-)
  • symblepharon (H11.23-)
  • code to identify percentage of skin exfoliation (L49.-)

Broader instructions also apply from L49-L54 Urticaria and erythema and Chapter 12: Diseases of the skin and subcutaneous tissue.

Alphabetic index entries

4 entries

Terms in the official ICD-10-CM index that lead to L51.2.

Codes whose notes reference L51.2

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 09 · Diseases and Disorders of the Skin, Subcutaneous Tissue and Breast

ICD-9-CM equivalent

Converter →
  • 695.15Toxic epidermal necrolysisapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about L51.2

Is L51.2 billable?

Yes. L51.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can L51.2 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict L51.2 as a principal diagnosis.

Is L51.2 a CC or MCC?

L51.2 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does L51.2 group to?

L51.2 is used in the MS-DRG v44.0 logic for MS-DRG 595 (Major Skin Disorders with MCC) and MS-DRG 596 (Major Skin Disorders without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for L51.2?

The CMS General Equivalence Mappings map L51.2 to ICD-9-CM 695.15.