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ICD-10-CM 2027

ICD-10 code for nervous trouble

R45.0

Nervousness

✓ Billable / specific

From the official ICD-10-CM alphabetic index entry “Trouble › nervous”. Page updated September 29, 2026.

About coding nervous trouble

The ICD-10-CM code for nervous trouble is R45.0 (Nervousness).

Within R45 (symptoms and signs involving emotional state), R45.0 is specifically for Nervousness. Related codes cover Restlessness and agitation (R45.1), unhappiness (R45.2), Demoralization and apathy (R45.3), irritability and anger (R45.4), Hostility (R45.5), Violent behavior (R45.6), state of emotional shock and stress, unspecified (R45.7) and other symptoms and signs involving emotional state (R45.8).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 880 (Acute Adjustment Reaction and Psychosocial Dysfunction, relative weight 0.9306), in MDC 19 (Mental Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about nervous trouble ICD-10 codes

What is the ICD-10 code for nervous trouble?

R45.0 — Nervousness.

Is R45.0 billable?

Yes. R45.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can R45.0 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict R45.0 as a principal diagnosis.

Is R45.0 a CC or MCC?

No. R45.0 is neither a CC nor an MCC under MS-DRG v44.0.