ICD-10-CM 2027
ICD-10 code for Neurasthenia
From the official ICD-10-CM alphabetic index entry “Neurasthenia”. Page updated September 29, 2026.
About coding Neurasthenia
The ICD-10-CM code for Neurasthenia is F48.8 (Other specified nonpsychotic mental disorders). The official index lists 3 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on F48.8.
Within F48, choose F48.8 (Other specified nonpsychotic mental disorders) only when documentation doesn't support a more specific option: Depersonalization-derealization syndrome (F48.1), Pseudobulbar affect (F48.2) and nonpsychotic mental disorder, unspecified (F48.9).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 882 (Neuroses Except Depressive, relative weight 0.9952), in MDC 19 (Mental Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Neurasthenia codes (official index)
Common questions about Neurasthenia ICD-10 codes
What is the ICD-10 code for Neurasthenia?
- F48.8 — Other specified nonpsychotic mental disorders. More specific codes apply when the documentation supports them: F45.8, F45.8, F45.8.
What is the ICD-10 code for cardiac neurasthenia?
- F45.8 — Other somatoform disorders.
What is the ICD-10 code for gastric neurasthenia?
- F45.8 — Other somatoform disorders.
What is the ICD-10 code for heart neurasthenia?
- F45.8 — Other somatoform disorders.
Is F48.8 billable?
- Yes. F48.8 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can F48.8 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict F48.8 as a principal diagnosis.
Is F48.8 a CC or MCC?
- No. F48.8 is neither a CC nor an MCC under MS-DRG v44.0.