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ICD-10-CM 2027

ICD-10 code for nodosa simplex struma

E04.9

Nontoxic goiter, unspecified

✓ Billable / specific

From the official ICD-10-CM alphabetic index entry “Struma › nodosa (simplex)”. Page updated September 29, 2026.

About coding nodosa simplex struma

The ICD-10-CM code for nodosa simplex struma is E04.9 (Nontoxic goiter, unspecified). The official index lists 17 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E04.9.

Within E04, choose E04.9 (Nontoxic goiter, unspecified) only when documentation doesn't support a more specific option: nontoxic diffuse goiter (E04.0), nontoxic single thyroid nodule (E04.1), nontoxic multinodular goiter (E04.2) and other specified nontoxic goiter (E04.8).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

More specific nodosa simplex struma codes (official index)

  • endemic E01.2 — Iodine-deficiency related (endemic) goiter, unspecified
  • multinodular E01.1 — Iodine-deficiency related multinodular (endemic) goiter
  • multinodular E04.2 — Nontoxic multinodular goiter
  • iodine-deficiency related E01.1 — Iodine-deficiency related multinodular (endemic) goiter
  • toxic or with hyperthyroidism E05.20 — Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm
  • with thyroid storm E05.21 — Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm
  • multinodular E05.20 — Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm
  • with thyroid storm E05.21 — Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm
  • uninodular E05.10 — Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm
  • with thyroid storm E05.11 — Thyrotoxicosis with toxic single thyroid nodule with thyrotoxic crisis or storm
  • toxicosa E05.20 — Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm
  • with thyroid storm E05.21 — Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm
  • multinodular E05.20 — Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm
  • with thyroid storm E05.21 — Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm
  • uninodular E05.10 — Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm
  • with thyroid storm E05.11 — Thyrotoxicosis with toxic single thyroid nodule with thyrotoxic crisis or storm
  • uninodular E04.1 — Nontoxic single thyroid nodule

Common questions about nodosa simplex struma ICD-10 codes

What is the ICD-10 code for nodosa simplex struma?

E04.9 — Nontoxic goiter, unspecified. More specific codes apply when the documentation supports them: E01.2, E01.1, E04.2, E01.1 and others below.

What is the ICD-10 code for endemic nodosa simplex struma?

E01.2 — Iodine-deficiency related (endemic) goiter, unspecified.

What is the ICD-10 code for multinodular nodosa simplex struma?

E04.2 — Nontoxic multinodular goiter.

What is the ICD-10 code for toxic or with hyperthyroidism nodosa simplex struma?

E05.20 — Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm.

What is the ICD-10 code for toxicosa nodosa simplex struma?

E05.20 — Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm.

What is the ICD-10 code for uninodular nodosa simplex struma?

E04.1 — Nontoxic single thyroid nodule.

Is E04.9 billable?

Yes. E04.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E04.9 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E04.9 as a principal diagnosis.

Is E04.9 a CC or MCC?

No. E04.9 is neither a CC nor an MCC under MS-DRG v44.0.