ICD-10-CM 2027
ICD-10 code for Orotaciduric anemia
From the official ICD-10-CM alphabetic index entry “Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › orotaciduric (congenital) (hereditary)”. Page updated September 29, 2026.
About coding Orotaciduric anemia
The ICD-10-CM code for Orotaciduric anemia is D53.0 (Protein deficiency anemia).
Within D53 (other nutritional anemias), D53.0 is specifically for protein deficiency anemia. Related codes cover other megaloblastic anemias, not elsewhere classified (D53.1), Scorbutic anemia (D53.2), other specified nutritional anemias (D53.8) and nutritional anemia, unspecified (D53.9).
Don't report D53.0 together with the conditions in its Excludes1 note: Lesch-Nyhan syndrome (E79.1).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Don't confuse with (Excludes1 for D53.0)
- Lesch-Nyhan syndrome (E79.1)
Common questions about Orotaciduric anemia ICD-10 codes
What is the ICD-10 code for Orotaciduric anemia?
- D53.0 — Protein deficiency anemia.
Is D53.0 billable?
- Yes. D53.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D53.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D53.0 as a principal diagnosis.
Is D53.0 a CC or MCC?
- No. D53.0 is neither a CC nor an MCC under MS-DRG v44.0.