ICD-10-CM 2027
ICD-10 code for Orotic aciduria
Other specified disorders of purine and pyrimidine metabolism
From the official ICD-10-CM alphabetic index entry “Aciduria › orotic (congenital) (hereditary) (pyrimidine deficiency)”. Page updated September 29, 2026.
About coding Orotic aciduria
The ICD-10-CM code for Orotic aciduria is E79.89 (Other specified disorders of purine and pyrimidine metabolism). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on E79.89.
Within E79.8, choose E79.89 (Other specified disorders of purine and pyrimidine metabolism) only when documentation doesn't support a more specific option: Aicardi-Goutieres syndrome (E79.81) and hereditary xanthinuria (E79.82).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 642 (Inborn and Other Disorders of Metabolism, relative weight 1.3219), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Orotic aciduria codes (official index)
- anemia D53.0 — Protein deficiency anemia
Common questions about Orotic aciduria ICD-10 codes
What is the ICD-10 code for Orotic aciduria?
- E79.89 — Other specified disorders of purine and pyrimidine metabolism. More specific codes apply when the documentation supports them: D53.0.
What is the ICD-10 code for anemia orotic aciduria?
- D53.0 — Protein deficiency anemia.
Is E79.89 billable?
- Yes. E79.89 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E79.89 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E79.89 as a principal diagnosis.
Is E79.89 a CC or MCC?
- E79.89 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.