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ICD-10-CM 2027 diagnosis code

E79.89Other specified disorders of purine and pyrimidine metabolism

✓ Billable / specificCC — complication/comorbidity

E79.89 is a valid, billable ICD-10-CM code for other specified disorders of purine and pyrimidine metabolism. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Oth disrd of purine and pyrimidine metabolism

Looking up by condition? See ICD-10 code for Orotaciduria.

Code last changed in FY2024 (effective October 1, 2023). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E79.89

E79.89 is the ICD-10-CM diagnosis code for other specified disorders of purine and pyrimidine metabolism. It belongs to category E79 (disorders of purine and pyrimidine metabolism), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E79.8, choose E79.89 (Other specified disorders of purine and pyrimidine metabolism) only when documentation doesn't support a more specific option: Aicardi-Goutieres syndrome (E79.81) and hereditary xanthinuria (E79.82).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 642 (Inborn and Other Disorders of Metabolism, relative weight 1.3219), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It was added in FY2024, effective October 1, 2023.

Notes that apply from higher levels

Instructions written at a parent level also apply to E79.89.

› From E79 Disorders of purine and pyrimidine metabolism
Excludes1
  • Ataxia-telangiectasia (Q87.19)
  • Bloom's syndrome (Q82.8)
  • Cockayne's syndrome (Q87.19)
  • calculus of kidney (N20.0)
  • combined immunodeficiency disorders (D81.-)
  • Fanconi's anemia (D61.09)
  • gout (M1A.-, M10.-)
  • orotaciduric anemia (D53.0)
  • progeria (E34.8)
  • Werner's syndrome (E34.8)
  • xeroderma pigmentosum (Q82.1)

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

Alphabetic index entries

4 entries

Terms in the official ICD-10-CM index that lead to E79.89.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 10 · Endocrine, Nutritional and Metabolic Diseases and Disorders

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2024 (effective 10/1/2023): Added
  • No changes since FY2024.

Common questions about E79.89

Is E79.89 billable?

Yes. E79.89 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E79.89 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E79.89 as a principal diagnosis.

Is E79.89 a CC or MCC?

E79.89 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does E79.89 group to?

E79.89 is used in the MS-DRG v44.0 logic for MS-DRG 642 (Inborn and Other Disorders of Metabolism). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.