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ICD-10-CM 2027

ICD-10 code for plaques sclerosis

G35.D

Multiple sclerosis, unspecified

✓ Billable / specific

From the official ICD-10-CM alphabetic index entry “Sclerosis, sclerotic › plaques”. Page updated September 29, 2026.

About coding plaques sclerosis

The ICD-10-CM code for plaques sclerosis is G35.D (Multiple sclerosis, unspecified).

Within G35, choose G35.D (unspecified) only when documentation doesn't support a more specific option: Relapsing-remitting multiple sclerosis (G35.A), primary progressive multiple sclerosis (G35.B) and secondary progressive multiple sclerosis (G35.C).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 058 (Multiple Sclerosis and Cerebellar Ataxia with MCC, relative weight 1.8438), DRG 059 (Multiple Sclerosis and Cerebellar Ataxia with CC, relative weight 1.2002) and DRG 060 (Multiple Sclerosis and Cerebellar Ataxia without CC/MCC, relative weight 0.9247), in MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about plaques sclerosis ICD-10 codes

What is the ICD-10 code for plaques sclerosis?

G35.D — Multiple sclerosis, unspecified.

Is G35.D billable?

Yes. G35.D is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can G35.D be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict G35.D as a principal diagnosis.

Is G35.D a CC or MCC?

No. G35.D is neither a CC nor an MCC under MS-DRG v44.0.