ICD-10-CM 2027 diagnosis code

G35Multiple sclerosis

Not billable — use a more specific code

G35 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it.

Code last changed in FY2026 (effective October 1, 2025). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About G35

G35 is the ICD-10-CM diagnosis code for multiple sclerosis. It belongs to block G35-G37 (demyelinating diseases of the central nervous system) and chapter 6 (diseases of the nervous system). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: G35.A (sclerosis), G35.B (sclerosis), G35.C (sclerosis) and G35.D (unspecified).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2026 (expanded into subcodes).

Before ICD-10, this condition was coded in ICD-9-CM as 340 (multiple sclerosis).

Specific codes under G35

Notes that apply from higher levels

Instructions written at a parent level also apply to G35.

Broader instructions also apply from Chapter 6: Diseases of the nervous system.

Codes whose notes reference G35

F02Code first
F48.2Code first
G04Excludes2
G37.3Excludes1

ICD-9-CM equivalent

Converter →

340Multiple sclerosisexact

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027

FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
FY2026 (effective 10/1/2025): Expanded — no longer billable

Common questions about G35

Is G35 billable?: No. G35 is a header code. Report one of its more specific subcodes instead.
What is the ICD-9 code for G35?: The CMS General Equivalence Mappings map G35 to ICD-9-CM 340.