ICD-10-CM 2027
ICD-10 code for Plasmacytopenia
From the official ICD-10-CM alphabetic index entry “Plasmacytopenia”. Page updated September 29, 2026.
About coding Plasmacytopenia
The ICD-10-CM code for Plasmacytopenia is D72.818 (Other decreased white blood cell count).
Within D72.81, choose D72.818 (Other decreased white blood cell count) only when documentation doesn't support a more specific option: Lymphocytopenia (D72.810) and unspecified (D72.819).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 814 (Reticuloendothelial and Immunity Disorders with MCC, relative weight 2.0729), DRG 815 (Reticuloendothelial and Immunity Disorders with CC, relative weight 1.0444) and DRG 816 (Reticuloendothelial and Immunity Disorders without CC/MCC, relative weight 0.7381), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Plasmacytopenia ICD-10 codes
What is the ICD-10 code for Plasmacytopenia?
- D72.818 — Other decreased white blood cell count.
Is D72.818 billable?
- Yes. D72.818 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D72.818 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D72.818 as a principal diagnosis.
Is D72.818 a CC or MCC?
- No. D72.818 is neither a CC nor an MCC under MS-DRG v44.0.