ICD-10-CM 2027
ICD-10 code for premature menopause
From the official ICD-10-CM alphabetic index entry “Menopause, menopausal (asymptomatic) (state) › premature”. Page updated September 29, 2026.
About coding premature menopause
The ICD-10-CM code for premature menopause is E28.319 (Asymptomatic premature menopause). The official index lists 6 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E28.319.
Within E28.31 (premature menopause), E28.319 is specifically for Asymptomatic premature menopause. Related codes cover symptomatic premature menopause (E28.310).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 742 (Uterine and Adnexa Procedures for Non-Malignancy with CC/MCC, relative weight 1.8456), DRG 743 (Uterine and Adnexa Procedures for Non-Malignancy without CC/MCC, relative weight 1.2974), DRG 760 (Menstrual and Other Female Reproductive System Disorders with CC/MCC, relative weight 1.0129) and DRG 761 (Menstrual and Other Female Reproductive System Disorders without CC/MCC, relative weight 0.7041), in MDC 13 (Diseases and Disorders of the Female Reproductive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific premature menopause codes (official index)
- asymptomatic E28.319 — Asymptomatic premature menopause
- postirradiation E89.40 — Asymptomatic postprocedural ovarian failure
- postsurgical E89.40 — Asymptomatic postprocedural ovarian failure
- symptomatic E28.310 — Symptomatic premature menopause
- postirradiation E89.41 — Symptomatic postprocedural ovarian failure
- postsurgical E89.41 — Symptomatic postprocedural ovarian failure
Common questions about premature menopause ICD-10 codes
What is the ICD-10 code for premature menopause?
- E28.319 — Asymptomatic premature menopause. More specific codes apply when the documentation supports them: E28.319, E89.40, E89.40, E28.310 and others below.
What is the ICD-10 code for asymptomatic premature menopause?
- E28.319 — Asymptomatic premature menopause.
What is the ICD-10 code for symptomatic premature menopause?
- E28.310 — Symptomatic premature menopause.
Is E28.319 billable?
- Yes. E28.319 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E28.319 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E28.319 as a principal diagnosis.
Is E28.319 a CC or MCC?
- No. E28.319 is neither a CC nor an MCC under MS-DRG v44.0.