ICD-10-CM 2027 diagnosis code

E28.31Premature menopause

Not billable — use a more specific code

E28.31 is a header code, so it can't be reported by itself. Choose one of the 2 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E28.31

E28.31 is the ICD-10-CM diagnosis code for premature menopause. It belongs to category E28 (ovarian dysfunction), block E20-E35 (disorders of other endocrine glands) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 2 subcodes must be used instead.

Within E28.3 (primary ovarian failure), E28.31 is specifically for premature menopause. Related codes cover other primary ovarian failure (E28.39).

To report this condition, pick the subcode that matches the documentation: E28.310 (menopause) and E28.319 (menopause).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under E28.31

Notes that apply from higher levels

Instructions written at a parent level also apply to E28.31.

› From E28.3 Primary ovarian failure

Excludes1

pure gonadal dysgenesis (Q99.1)
Turner's syndrome (Q96.-)

› From E28 Ovarian dysfunction

Excludes1

isolated gonadotropin deficiency (E23.0)
postprocedural ovarian failure (E89.4-)

Broader instructions also apply from E20-E35 Disorders of other endocrine glands and Chapter 4: Endocrine, nutritional and metabolic diseases.

Codes whose notes reference E28.31

N95Excludes1
N95Excludes1
Z91.BCode also

Code history

2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027

FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
No changes since FY2016.

Common questions about E28.31

Is E28.31 billable?: No. E28.31 is a header code. Report one of its more specific subcodes instead.