ICD-10-CM 2027
ICD-10 code for Sandhoff's disease
From the official ICD-10-CM alphabetic index entry “Sandhoff's disease”. Page updated September 29, 2026.
About coding Sandhoff's disease
The ICD-10-CM code for Sandhoff's disease is E75.01 (Sandhoff disease).
Within E75.0 (GM2 gangliosidosis), E75.01 is specifically for Sandhoff disease. Related codes cover unspecified (E75.00), Tay-Sachs disease (E75.02) and other GM2 gangliosidosis (E75.09).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 056 (Degenerative Nervous System Disorders with MCC, relative weight 2.2655) and DRG 057 (Degenerative Nervous System Disorders without MCC, relative weight 1.2838), in MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Sandhoff's disease ICD-10 codes
What is the ICD-10 code for Sandhoff's disease?
- E75.01 — Sandhoff disease.
Is E75.01 billable?
- Yes. E75.01 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E75.01 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E75.01 as a principal diagnosis.
Is E75.01 a CC or MCC?
- E75.01 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.