ICD-10-CM 2027 diagnosis code
E75.0GM2 gangliosidosis
E75.0 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About E75.0
E75.0 is the ICD-10-CM diagnosis code for GM2 gangliosidosis. It belongs to category E75 (disorders of sphingolipid metabolism and other lipid storage disorders), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.
Within E75 (disorders of sphingolipid metabolism and other lipid storage disorders), E75.0 is specifically for GM2 gangliosidosis. Related codes cover other and unspecified gangliosidosis (E75.1), other sphingolipidosis (E75.2), sphingolipidosis, unspecified (E75.3), Neuronal ceroid lipofuscinosis (E75.4), other lipid storage disorders (E75.5) and lipid storage disorder, unspecified (E75.6).
To report this condition, pick the subcode that matches the documentation: E75.00 (unspecified), E75.01 (disease), E75.02 (disease) and E75.09 (gangliosidosis).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under E75.0
Notes that apply from higher levels
Instructions written at a parent level also apply to E75.0.
Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.
Codes whose notes reference E75.0
- E78Excludes1
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about E75.0
Is E75.0 billable?
- No. E75.0 is a header code. Report one of its more specific subcodes instead.