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ICD-10-CM 2027

ICD-10 code for senile systemic SSA amyloidosis

E85.82

Wild-type transthyretin-related (ATTR) amyloidosis

✓ Billable / specificCC — complication/comorbidity

From the official ICD-10-CM alphabetic index entry “Amyloidosis (generalized) (primary) › senile systemic (SSA)”. Page updated September 29, 2026.

About coding senile systemic SSA amyloidosis

The ICD-10-CM code for senile systemic SSA amyloidosis is E85.82 (Wild-type transthyretin-related (ATTR) amyloidosis).

Within E85.8 (other amyloidosis), E85.82 is specifically for Wild-type transthyretin-related (ATTR) amyloidosis. Related codes cover light chain (AL) amyloidosis (E85.81) and other amyloidosis (E85.89).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 545 (Connective Tissue Disorders with MCC, relative weight 2.3892), DRG 546 (Connective Tissue Disorders with CC, relative weight 1.1745) and DRG 547 (Connective Tissue Disorders without CC/MCC, relative weight 0.7526), in MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about senile systemic SSA amyloidosis ICD-10 codes

What is the ICD-10 code for senile systemic SSA amyloidosis?

E85.82 — Wild-type transthyretin-related (ATTR) amyloidosis.

Is E85.82 billable?

Yes. E85.82 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E85.82 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E85.82 as a principal diagnosis.

Is E85.82 a CC or MCC?

E85.82 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.