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ICD-10-CM 2027 diagnosis code

E85.8Other amyloidosis

Not billable — use a more specific code

E85.8 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it.

Code last changed in FY2018 (effective October 1, 2017). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E85.8

E85.8 is the ICD-10-CM diagnosis code for other amyloidosis. It belongs to category E85 (amyloidosis), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within E85, choose E85.8 (Other amyloidosis) only when documentation doesn't support a more specific option: Non-neuropathic heredofamilial amyloidosis (E85.0), neuropathic heredofamilial amyloidosis (E85.1), heredofamilial amyloidosis, unspecified (E85.2), secondary systemic amyloidosis (E85.3), Organ-limited amyloidosis (E85.4) and unspecified (E85.9).

To report this condition, pick the subcode that matches the documentation: E85.81 (amyloidosis), E85.82 (amyloidosis) and E85.89 (amyloidosis).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2018 (expanded into subcodes).

Specific codes under E85.8

Notes that apply from higher levels

Instructions written at a parent level also apply to E85.8.

› From E85 Amyloidosis
Excludes2

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • FY2018 (effective 10/1/2017): Expanded — no longer billable

Common questions about E85.8

Is E85.8 billable?

No. E85.8 is a header code. Report one of its more specific subcodes instead.