ICD-10-CM 2027
ICD-10 code for sepsis
Confirmed by the official ICD-10-CM index entry “disorder (of) › glomerular (in) › sepsis nec”. Page updated September 29, 2026.
About coding sepsis
The ICD-10-CM code for sepsis is A41.9 (Sepsis, unspecified organism). The official index lists 19 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on A41.9.
It is also searched as septicemia.
Within A41, choose A41.9 (Sepsis, unspecified organism) only when documentation doesn't support a more specific option: sepsis due to Staphylococcus aureus (A41.0), sepsis due to other specified staphylococcus (A41.1), sepsis due to unspecified staphylococcus (A41.2), sepsis due to Hemophilus influenzae (A41.3), sepsis due to anaerobes (A41.4), sepsis due to other Gram-negative organisms (A41.5) and other specified sepsis (A41.8).
Code first: , if applicable, postprocedural sepsis (T81.44-), sepsis due to central venous catheter (T80.211-), sepsis during labor (O75.3), sepsis following abortion, ectopic or molar pregnancy (O03.37, O03.87, O04.87, O07.37, O08.82) and 2 more.
As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.
Related Sepsis codes
- A40.0 Sepsis due to streptococcus, group A
- A40.1 Sepsis due to streptococcus, group B
- A40.3 Sepsis due to Streptococcus pneumoniae
- A40.8 Other streptococcal sepsis
- A40.9 Streptococcal sepsis, unspecified
- A41.01 Sepsis due to Methicillin susceptible Staphylococcus aureus
- A41.02 Sepsis due to Methicillin resistant Staphylococcus aureus
- A41.1 Sepsis due to other specified staphylococcus
- A41.2 Sepsis due to unspecified staphylococcus
- A41.3 Sepsis due to Hemophilus influenzae
- A41.4 Sepsis due to anaerobes
- A41.50 Gram-negative sepsis, unspecified
- A41.51 Sepsis due to Escherichia coli [E. coli]
- A41.52 Sepsis due to Pseudomonas
- A41.53 Sepsis due to Serratia
- A41.54 Sepsis due to Acinetobacter baumannii
- A41.59 Other Gram-negative sepsis
- A41.81 Sepsis due to Enterococcus
- A41.89 Other specified sepsis
Common questions about sepsis ICD-10 codes
What is the ICD-10 code for sepsis?
- A41.9 — Sepsis, unspecified organism. More specific codes apply when the documentation supports them: A40.0, A40.1, A40.3, A40.8 and others below.
What is the ICD-10 code for sepsis due to streptococcus, group a?
- A40.0 — Sepsis due to streptococcus, group A.
What is the ICD-10 code for sepsis due to streptococcus, group b?
- A40.1 — Sepsis due to streptococcus, group B.
What is the ICD-10 code for sepsis due to streptococcus pneumoniae?
- A40.3 — Sepsis due to Streptococcus pneumoniae.
What is the ICD-10 code for other streptococcal sepsis?
- A40.8 — Other streptococcal sepsis.
What is the ICD-10 code for streptococcal sepsis, unspecified?
- A40.9 — Streptococcal sepsis, unspecified.
What is the ICD-10 code for sepsis due to methicillin susceptible staphylococcus aureus?
- A41.01 — Sepsis due to Methicillin susceptible Staphylococcus aureus.
Is A41.9 billable?
- Yes. A41.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can A41.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict A41.9 as a principal diagnosis.
Is A41.9 a CC or MCC?
- A41.9 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.