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ICD-10-CM 2027

ICD-10 code for septic encephalopathy

G93.41

Metabolic encephalopathy

From the official ICD-10-CM alphabetic index entry “Encephalopathy (acute) › septic”. Page updated September 29, 2026.

About coding septic encephalopathy

The ICD-10-CM code for septic encephalopathy is G93.41 (Metabolic encephalopathy).

Within G93.4 (other and unspecified encephalopathy), G93.41 is specifically for metabolic encephalopathy. Related codes cover encephalopathy, unspecified (G93.40), Megalencephalic leukoencephalopathy with subcortical cysts (G93.42), leukoencephalopathy with calcifications and cysts (G93.43), Adult-onset leukodystrophy with axonal spheroids (G93.44), developmental and epileptic encephalopathy (G93.45) and other encephalopathy (G93.49).

As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 070 (Other Cerebrovascular Disorders with MCC, relative weight 1.6093), DRG 071 (Other Cerebrovascular Disorders with CC, relative weight 1.0177), DRG 072 (Other Cerebrovascular Disorders without CC/MCC, relative weight 0.7348), DRG 974 (HIV with Major Related Condition with MCC, relative weight 3.0506), DRG 975 (HIV with Major Related Condition with CC, relative weight 1.3252) and DRG 976 (HIV with Major Related Condition without CC/MCC, relative weight 0.8124), in MDC 01 (Diseases and Disorders of the Nervous System) and MDC 25 (Human Immunodeficiency Virus Infections), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about septic encephalopathy ICD-10 codes

What is the ICD-10 code for septic encephalopathy?

G93.41 — Metabolic encephalopathy.

Is G93.41 billable?

Yes. G93.41 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can G93.41 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict G93.41 as a principal diagnosis.

Is G93.41 a CC or MCC?

G93.41 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.