ICD-10-CM 2027
ICD-10 code for Staphylococcemia
Sepsis due to unspecified staphylococcus
From the official ICD-10-CM alphabetic index entry “Staphylococcemia”. Page updated September 29, 2026.
About coding Staphylococcemia
The ICD-10-CM code for Staphylococcemia is A41.2 (Sepsis due to unspecified staphylococcus).
Within A41, choose A41.2 (Sepsis due to unspecified staphylococcus) only when documentation doesn't support a more specific option: sepsis due to Staphylococcus aureus (A41.0), sepsis due to other specified staphylococcus (A41.1), sepsis due to Hemophilus influenzae (A41.3), sepsis due to anaerobes (A41.4), sepsis due to other Gram-negative organisms (A41.5), other specified sepsis (A41.8) and sepsis, unspecified organism (A41.9).
Code first: , if applicable, postprocedural sepsis (T81.44-), sepsis due to central venous catheter (T80.211-), sepsis during labor (O75.3), sepsis following abortion, ectopic or molar pregnancy (O03.37, O03.87, O04.87, O07.37, O08.82) and 2 more.
As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.
Common questions about Staphylococcemia ICD-10 codes
What is the ICD-10 code for Staphylococcemia?
- A41.2 — Sepsis due to unspecified staphylococcus.
Is A41.2 billable?
- Yes. A41.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can A41.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict A41.2 as a principal diagnosis.
Is A41.2 a CC or MCC?
- A41.2 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.