ICD-10 code for thrombotic microangiopathy

The ICD-10-CM code for thrombotic microangiopathy is M31.10 (Thrombotic microangiopathy, unspecified). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on M31.10.

Within M31.1, choose M31.10 (unspecified) only when documentation doesn't support a more specific option: hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA] (M31.11) and other thrombotic microangiopathy (M31.19).

As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 545 (Connective Tissue Disorders with MCC, relative weight 2.3892), DRG 546 (Connective Tissue Disorders with CC, relative weight 1.1745) and DRG 547 (Connective Tissue Disorders without CC/MCC, relative weight 0.7526), in MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.