ICD-10-CM 2027
ICD-10 code for toxic anemia
Aplastic anemia due to other external agents
From the official ICD-10-CM alphabetic index entry “Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › toxic”. Page updated September 29, 2026.
About coding toxic anemia
The ICD-10-CM code for toxic anemia is D61.2 (Aplastic anemia due to other external agents).
Within D61, choose D61.2 (Aplastic anemia due to other external agents) only when documentation doesn't support a more specific option: constitutional aplastic anemia (D61.0), drug-induced aplastic anemia (D61.1), idiopathic aplastic anemia (D61.3), other specified aplastic anemias and other bone marrow failure syndromes (D61.8) and aplastic anemia, unspecified (D61.9).
Code first: , if applicable, toxic effects of substances chiefly nonmedicinal as to source (T51-T65).
As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.
Common questions about toxic anemia ICD-10 codes
What is the ICD-10 code for toxic anemia?
- D61.2 — Aplastic anemia due to other external agents.
Is D61.2 billable?
- Yes. D61.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D61.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D61.2 as a principal diagnosis.
Is D61.2 a CC or MCC?
- D61.2 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.