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ICD-10-CM 2027 diagnosis code

T65Toxic effect of other and unspecified substances

Not billable — use a more specific code

T65 is a header code, so it can't be reported by itself. Choose one of the 9 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About T65

T65 is the ICD-10-CM diagnosis code for toxic effect of other and unspecified substances. It belongs to block T51-T65 (toxic effects of substances chiefly nonmedicinal as to source) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 9 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: T65.0 (cyanides), T65.1 (salts), T65.2 (nicotine), T65.3 (homologues), T65.4 (disulfide), T65.5 (esters), T65.6 (classified), T65.8 (substances) and 1 more.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under T65

Notes that apply from higher levels

Instructions written at a parent level also apply to T65.

Codes whose notes reference T65

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about T65

Is T65 billable?

No. T65 is a header code. Report one of its more specific subcodes instead.