ICD-10-CM 2027 diagnosis code
T65Toxic effect of other and unspecified substances
T65 is a header code, so it can't be reported by itself. Choose one of the 9 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T65
T65 is the ICD-10-CM diagnosis code for toxic effect of other and unspecified substances. It belongs to block T51-T65 (toxic effects of substances chiefly nonmedicinal as to source) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 9 subcodes must be used instead.
To report this condition, pick the subcode that matches the documentation: T65.0 (cyanides), T65.1 (salts), T65.2 (nicotine), T65.3 (homologues), T65.4 (disulfide), T65.5 (esters), T65.6 (classified), T65.8 (substances) and 1 more.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under T65
- T65.0Toxic effect of cyanides
- T65.1Toxic effect of strychnine and its salts
- T65.2Toxic effect of tobacco and nicotine
- T65.3Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues
- T65.3XToxic effect of nitroderivatives and aminoderivatives of benzene and its homologues
- T65.3X1Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, accidental (unintentional)
- T65.3X2Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, intentional self-harm
- T65.3X3Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, assault
- T65.3X4Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, undetermined
- T65.3XToxic effect of nitroderivatives and aminoderivatives of benzene and its homologues
- T65.4Toxic effect of carbon disulfide
- T65.5Toxic effect of nitroglycerin and other nitric acids and esters
- T65.5XToxic effect of nitroglycerin and other nitric acids and esters
- T65.5X1Toxic effect of nitroglycerin and other nitric acids and esters, accidental (unintentional)
- T65.5X2Toxic effect of nitroglycerin and other nitric acids and esters, intentional self-harm
- T65.5X3Toxic effect of nitroglycerin and other nitric acids and esters, assault
- T65.5X4Toxic effect of nitroglycerin and other nitric acids and esters, undetermined
- T65.5XToxic effect of nitroglycerin and other nitric acids and esters
- T65.6Toxic effect of paints and dyes, not elsewhere classified
- T65.6XToxic effect of paints and dyes, not elsewhere classified
- T65.6X1Toxic effect of paints and dyes, not elsewhere classified, accidental (unintentional)
- T65.6X2Toxic effect of paints and dyes, not elsewhere classified, intentional self-harm
- T65.6X3Toxic effect of paints and dyes, not elsewhere classified, assault
- T65.6X4Toxic effect of paints and dyes, not elsewhere classified, undetermined
- T65.6XToxic effect of paints and dyes, not elsewhere classified
- T65.8Toxic effect of other specified substances
- T65.9Toxic effect of unspecified substance
Notes that apply from higher levels
Instructions written at a parent level also apply to T65.
Broader instructions also apply from T51-T65 Toxic effects of substances chiefly nonmedicinal as to source and Chapter 19: Injury, poisoning and certain other consequences of external causes.
Codes whose notes reference T65
- D61.2Code first
- D64.2Code first
- E03.2Code first
- E09Code first
- F02Code first
- G21.2Code first
- G62.2Code first
- G70.1Code first
- G72.2Code first
- G92.8Code first
- G92.9Code first
- H10.21Code first
- H35.38Code first
- H46.3Code first
- H91.0Code first
- I42.7Code first
- J68Code first
- J69.1Code first
- J69.8Code first
- J70.8Code first
- J70.9Code first
- J84.89Code first
- K22.1Code first
- K52.1Code first
- K59.3Code first
- K71Code first
- L53.0Code first
- M34.2Code first
- N14Code first
- P58.4Code first
- T20.4Code first
- T20.5Code first
- T20.6Code first
- T20.7Code first
- T21.4Code first
- T21.5Code first
- T21.6Code first
- T21.7Code first
- T22.4Code first
- T22.5Code first
- T22.6Code first
- T22.7Code first
- T23.4Code first
- T23.5Code first
- T23.6Code first
- T23.7Code first
- T24.4Code first
- T24.5Code first
- T24.6Code first
- T24.7Code first
- T25.4Code first
- T25.5Code first
- T25.6Code first
- T25.7Code first
- T26.5Code first
- T26.6Code first
- T26.7Code first
- T26.8Code first
- T26.9Code first
- T27.4Code first
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T65
Is T65 billable?
- No. T65 is a header code. Report one of its more specific subcodes instead.