ICD-10-CM 2027
ICD-10 code for Transcobalamine II anemia deficiency
From the official ICD-10-CM alphabetic index entry “Deficiency, deficient › transcobalamine II (anemia)”. Page updated September 29, 2026.
About coding Transcobalamine II anemia deficiency
The ICD-10-CM code for Transcobalamine II anemia deficiency is D51.2 (Transcobalamin II deficiency).
Within D51 (vitamin B12 deficiency anemia), D51.2 is specifically for Transcobalamin II deficiency. Related codes cover due to intrinsic factor deficiency (D51.0), due to selective vitamin B12 malabsorption with proteinuria (D51.1), other dietary vitamin B12 deficiency anemia (D51.3), other vitamin B12 deficiency anemias (D51.8) and unspecified (D51.9).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 811 (Red Blood Cell Disorders with MCC, relative weight 1.3988) and DRG 812 (Red Blood Cell Disorders without MCC, relative weight 0.9234), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Transcobalamine II anemia deficiency ICD-10 codes
What is the ICD-10 code for Transcobalamine II anemia deficiency?
- D51.2 — Transcobalamin II deficiency.
Is D51.2 billable?
- Yes. D51.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D51.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D51.2 as a principal diagnosis.
Is D51.2 a CC or MCC?
- No. D51.2 is neither a CC nor an MCC under MS-DRG v44.0.