ICD-10-CM 2027
ICD-10 code for transfusion complication
From the official ICD-10-CM alphabetic index entry “Complication (s) (from) (of) › transfusion (blood) (lymphocytes) (plasma)”. Page updated September 29, 2026.
About coding transfusion complication
The ICD-10-CM code for transfusion complication is T80.92 (Unspecified transfusion reaction). The official index lists 33 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on T80.92.
Within T80.9, choose T80.92 (Unspecified transfusion reaction) only when documentation doesn't support a more specific option: unspecified complication following infusion and therapeutic injection (T80.90) and hemolytic transfusion reaction, unspecified incompatibility (T80.91).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
More specific transfusion complication codes (official index)
- air embolism T80.0 — Air embolism following infusion, transfusion and therapeutic injection
- circulatory overload E87.71 — Transfusion associated circulatory overload
- febrile nonhemolytic transfusion reaction R50.84 — Febrile nonhemolytic transfusion reaction
- hemolysis T80.89 — Other complications following infusion, transfusion and therapeutic injection
- hemochromatosis E83.111 — Hemochromatosis due to repeated red blood cell transfusions
- hemolytic reaction (antigen unspecified) T80.919 — Hemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayed
- incompatibility reaction (antigen unspecified) T80.919 — Hemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayed
- ABO T80.30 — ABO incompatibility reaction due to transfusion of blood or blood products, unspecified
- delayed serologic (DSTR) T80.39 — Other ABO incompatibility reaction due to transfusion of blood or blood products
- hemolytic transfusion reaction (HTR) (unspecified time after transfusion) T80.319 — ABO incompatibility with hemolytic transfusion reaction, unspecified
- acute (AHTR) (less than 24 hours after transfusion) T80.310 — ABO incompatibility with acute hemolytic transfusion reaction
- delayed (DHTR) (24 hours or more after transfusion) T80.311 — ABO incompatibility with delayed hemolytic transfusion reaction
- specified NEC T80.39 — Other ABO incompatibility reaction due to transfusion of blood or blood products
- acute (antigen unspecified) T80.910 — Acute hemolytic transfusion reaction, unspecified incompatibility
- delayed (antigen unspecified) T80.911 — Delayed hemolytic transfusion reaction, unspecified incompatibility
- delayed serologic (DSTR) T80.89 — Other complications following infusion, transfusion and therapeutic injection
- Non-ABO (minor antigens (Duffy) (K) (Kell) (Kidd) (Lewis) (M) (N) (P) (S)) T80.A0 — Non-ABO incompatibility reaction due to transfusion of blood or blood products, unspecified
- delayed serologic (DSTR) T80.A9 — Other non-ABO incompatibility reaction due to transfusion of blood or blood products
- hemolytic transfusion reaction (HTR) (unspecified time after transfusion) T80.A19 — Non-ABO incompatibility with hemolytic transfusion reaction, unspecified
- acute (AHTR) (less than 24 hours after transfusion) T80.A10 — Non-ABO incompatibility with acute hemolytic transfusion reaction
- delayed (DHTR) (24 hours or more after transfusion) T80.A11 — Non-ABO incompatibility with delayed hemolytic transfusion reaction
- specified NEC T80.A9 — Other non-ABO incompatibility reaction due to transfusion of blood or blood products
- Rh (antigens (C) (c) (D) (E) (e)) (factor) T80.40 — Rh incompatibility reaction due to transfusion of blood or blood products, unspecified
- delayed serologic (DSTR) T80.49 — Other Rh incompatibility reaction due to transfusion of blood or blood products
- hemolytic transfusion reaction (HTR) (unspecified time after transfusion) T80.419 — Rh incompatibility with hemolytic transfusion reaction, unspecified
- acute (AHTR) (less than 24 hours after transfusion) T80.410 — Rh incompatibility with acute hemolytic transfusion reaction
- delayed (DHTR) (24 hours or more after transfusion) T80.411 — Rh incompatibility with delayed hemolytic transfusion reaction
- specified NEC T80.49 — Other Rh incompatibility reaction due to transfusion of blood or blood products
- infection T80.29 — Infection following other infusion, transfusion and therapeutic injection
- acute T80.22 — Acute infection following transfusion, infusion, or injection of blood and blood products
- reaction NEC T80.89 — Other complications following infusion, transfusion and therapeutic injection
- sepsis T80.29 — Infection following other infusion, transfusion and therapeutic injection
- shock T80.89 — Other complications following infusion, transfusion and therapeutic injection
Common questions about transfusion complication ICD-10 codes
What is the ICD-10 code for transfusion complication?
- T80.92 — Unspecified transfusion reaction (a header code; report a more specific subcode). More specific codes apply when the documentation supports them: T80.0, E87.71, R50.84, T80.89 and others below.
What is the ICD-10 code for air embolism transfusion complication?
- T80.0 — Air embolism following infusion, transfusion and therapeutic injection (header code; choose a more specific subcode).
What is the ICD-10 code for circulatory overload transfusion complication?
- E87.71 — Transfusion associated circulatory overload.
What is the ICD-10 code for febrile nonhemolytic transfusion reaction transfusion complication?
- R50.84 — Febrile nonhemolytic transfusion reaction.
What is the ICD-10 code for hemolysis transfusion complication?
- T80.89 — Other complications following infusion, transfusion and therapeutic injection (header code; choose a more specific subcode).
What is the ICD-10 code for hemochromatosis transfusion complication?
- E83.111 — Hemochromatosis due to repeated red blood cell transfusions.
What is the ICD-10 code for hemolytic reaction transfusion complication?
- T80.919 — Hemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayed (header code; choose a more specific subcode).
Is T80.92 billable?
- No. T80.92 is a header code. Report one of its more specific subcodes instead.