T80.91Hemolytic transfusion reaction, unspecified incompatibility

T80.91 is the ICD-10-CM diagnosis code for hemolytic transfusion reaction, unspecified incompatibility. It belongs to category T80 (complications following infusion, transfusion and therapeutic injection), block T80-T88 (complications of surgical and medical care, not elsewhere classified) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within T80.9, choose T80.91 (Hemolytic transfusion reaction, unspecified incompatibility) only when documentation doesn't support a more specific option: unspecified complication following infusion and therapeutic injection (T80.90) and unspecified transfusion reaction (T80.92).

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

Don't report T80.91 together with the conditions in its Excludes1 note: ABO incompatibility with hemolytic transfusion reaction (T80.31-), Non-ABO incompatibility with hemolytic transfusion reaction (T80.A1-) and Rh incompatibility with hemolytic transfusion reaction (T80.41-).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.