ICD-10-CM 2027
ICD-10 code for urticaria serum
From the official ICD-10-CM alphabetic index entry “Serum › urticaria”. Page updated September 29, 2026.
About coding urticaria serum
The ICD-10-CM code for urticaria serum is T80.69 (Other serum reaction due to other serum).
Within T80.6, choose T80.69 (other serum) only when documentation doesn't support a more specific option: administration of blood and blood products (T80.61) and vaccination (T80.62).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.