ICD-10-CM 2027
ICD-10 code for vascular syphilis
From the official ICD-10-CM alphabetic index entry “Syphilis, syphilitic (acquired) › vascular”. Page updated September 29, 2026.
About coding vascular syphilis
The ICD-10-CM code for vascular syphilis is A52.00 (Cardiovascular syphilis, unspecified). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on A52.00.
Within A52.0, choose A52.00 (Cardiovascular syphilis, unspecified) only when documentation doesn't support a more specific option: syphilitic aneurysm of aorta (A52.01), syphilitic aortitis (A52.02), syphilitic endocarditis (A52.03), syphilitic cerebral arteritis (A52.04), other cerebrovascular syphilis (A52.05), other syphilitic heart involvement (A52.06) and other cardiovascular syphilis (A52.09).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 314 (Other Circulatory System Diagnoses with MCC, relative weight 2.0873), DRG 315 (Other Circulatory System Diagnoses with CC, relative weight 0.9508) and DRG 316 (Other Circulatory System Diagnoses without CC/MCC, relative weight 0.6677), in MDC 05 (Diseases and Disorders of the Circulatory System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific vascular syphilis codes (official index)
- brain (cerebral) A52.05 — Other cerebrovascular syphilis
Common questions about vascular syphilis ICD-10 codes
What is the ICD-10 code for vascular syphilis?
- A52.00 — Cardiovascular syphilis, unspecified. More specific codes apply when the documentation supports them: A52.05.
What is the ICD-10 code for brain vascular syphilis?
- A52.05 — Other cerebrovascular syphilis.
Is A52.00 billable?
- Yes. A52.00 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can A52.00 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict A52.00 as a principal diagnosis.
Is A52.00 a CC or MCC?
- A52.00 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.