ICD-10-CM 2027
ICD-10 code for Vital depression
Major depressive disorder, recurrent severe without psychotic features
From the official ICD-10-CM alphabetic index entry “Depression (acute) (mental) › vital (recurrent) (without psychotic symptoms)”. Page updated September 29, 2026.
About coding Vital depression
The ICD-10-CM code for Vital depression is F33.2 (Major depressive disorder, recurrent severe without psychotic features). The official index lists 2 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on F33.2.
Within F33, choose F33.2 (severe without psychotic features) only when documentation doesn't support a more specific option: mild (F33.0), moderate (F33.1), severe with psychotic symptoms (F33.3), in remission (F33.4), other recurrent depressive disorders (F33.8) and unspecified (F33.9).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 885 (Psychoses, relative weight 1.3901), in MDC 19 (Mental Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Vital depression codes (official index)
Common questions about Vital depression ICD-10 codes
What is the ICD-10 code for Vital depression?
- F33.2 — Major depressive disorder, recurrent severe without psychotic features. More specific codes apply when the documentation supports them: F33.3, F32.2.
What is the ICD-10 code for single episode vital depression?
- F32.2 — Major depressive disorder, single episode, severe without psychotic features.
Is F33.2 billable?
- Yes. F33.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can F33.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict F33.2 as a principal diagnosis.
Is F33.2 a CC or MCC?
- F33.2 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.