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ICD-10-PCS 2027 procedure code

00P00KZRemoval of Nonautologous Tissue Substitute from Brain, Open Approach

✓ Valid for 2027O.R. procedure

Short description: Removal of Nonaut Sub from Brain, Open Approach

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 00P00KZ

00P00KZ is the ICD-10-PCS code for a removal procedure on the brain using an open approach with nonautologous tissue substitute. In ICD-10-PCS, removal means taking out or off a device from a body part.

In plain terms, this corresponds to other incision of brain, the ICD-9-CM procedure title it maps to (01.39).

For a different body part, codes include 00P20KZ (dura mater), 00PT0KZ (spinal meninges) and 00PV0KZ (spinal cord).

The same procedure with a different approach is coded 00P03KZ (percutaneous) and 00P04KZ (percutaneous endoscopic).

With a different device, use 00P000Z (drainage device), 00P002Z (monitoring device), 00P003Z (infusion device), 00P007Z (autologous tissue substitute), 00P00JZ (synthetic substitute), 00P00MZ (neurostimulator lead) and 1 more.

It is an operating-room procedure in the MS-DRG logic for DRG 023 (Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis with MCC or Antineoplastic Implant or Epilepsy with Neurostimulator), DRG 024 (Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis without MCC), DRG 025 (Craniotomy and Endovascular Intracranial Procedures with MCC), DRG 026 (Craniotomy and Endovascular Intracranial Procedures with CC), DRG 027 (Craniotomy and Endovascular Intracranial Procedures without CC/MCC) and DRG 907 (Other O.R. Procedures for Injuries with MCC), under the surgical categories “Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis”, “Craniotomy and endovascular intracranial procedures”, “Other O.R. Procedures for Injuries” and 1 more.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section
0Medical and Surgical
2. Body System
0Central Nervous System and Cranial Nerves
3. Operation
PRemoval

Taking out or off a device from a body part

If a device is taken out and a similar device put in without cutting or puncturing the skin or mucous membrane, the procedure is coded to the root operation CHANGE. Otherwise, the procedure for taking out a device is coded to the root operation REMOVAL

Includes: Drainage tube removal, cardiac pacemaker removal

4. Body Part
0Brain

Includes: Cerebrum; Corpus callosum; Encephalon

5. Approach
0Open

Cutting through the skin or mucous membrane and any other body layers necessary to expose the site of the procedure

6. Device
KNonautologous Tissue Substitute

Includes: Acellular Hydrated Dermis; Bone bank bone graft; Cook Biodesign(R) Fistula Plug(s); Cook Biodesign(R) Hernia Graft(s); Cook Biodesign(R) Layered Graft(s); Cook Zenapro(tm) Layered Graft(s); Fish skin; Kerecis(R) (GraftGuide) (MariGen) (SurgiBind) (SurgiClose); MIRODERM(tm) Biologic Wound Matrix; Piscine skin; Tissue bank graft

7. Qualifier
ZNo Qualifier

Other versions of this procedure

MS-DRG v44.0 grouping

All DRGs →

Surgical MS-DRGs this procedure can group to, depending on the principal diagnosis's MDC.

MDC 24 · Multiple Significant Trauma · Craniotomy for Multiple Significant Trauma

ICD-9-CM equivalent

Converter →
  • 01.39Other incision of brainapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about 00P00KZ

Is 00P00KZ a valid ICD-10-PCS code for 2027?

Yes. 00P00KZ is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

Is 00P00KZ an O.R. procedure?

Yes. 00P00KZ is an O.R. procedure in MS-DRG v44.0.

What DRG does 00P00KZ group to?

Depending on the principal diagnosis, 00P00KZ can group to MS-DRG 023, MS-DRG 024, MS-DRG 025, MS-DRG 026, MS-DRG 027 and MS-DRG 907.

What is the ICD-9 procedure code for 00P00KZ?

The CMS GEMs map 00P00KZ to ICD-9-CM 01.39 (Other incision of brain).