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ICD-10-PCS 2027 procedure code

3E00XGCIntroduction of Other Therapeutic Substance into Skin and Mucous Membranes, External Approach

✓ Valid for 2027

Short description: Introduce Oth Therap Subst in Skin/Mucous Mem, Extern

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E00XGC

3E00XGC is the ICD-10-PCS code for a introduction procedure on the skin and mucous membranes using an external approach with other therapeutic substance (qualifier: other substance). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to injection of therapeutic agent into breast, Iontophoresis and Non-invasive placement of bone growth stimulator, the ICD-9-CM procedure titles it maps to (85.92, 99.27 and 99.86).

For a different body part, codes include 3E09XGC (nose), 3E0BXGC (ear), 3E0CXGC (eye) and 3E0DXGC (mouth and pharynx).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
0Skin and Mucous Membranes
5. Approach
XExternal

Procedures performed directly on the skin or mucous membrane and procedures performed indirectly by the application of external force through the skin or mucous membrane

6. Substance
GOther Therapeutic Substance

Includes: Anacaulase-bcdb; Bromelain-enriched Proteolytic Enzyme; Collagenase SANTYL Ointment; COSELA(tm) (Trilaciclib); ENSPRYNG(tm) (Satralizumab-mwge); Fostamatinib; Idarucizumab, Pradaxa(R)(dabigatran) reversal agent; NexoBrid(tm); Praxbind(R) (idarucizumab), Pradaxa(R)(dabigatran) reversal agent; SANTYL Ointment; Satralizumab-mwge; TAVALISSE(R); Trilaciclib

7. Qualifier
COther Substance

Other versions of this procedure

Different qualifier

ICD-9-CM equivalent

Converter →
  • 85.92Injection of therapeutic agent into breastapproximate
  • 99.27Iontophoresisapproximate
  • 99.86Non-invasive placement of bone growth stimulatorapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about 3E00XGC

Is 3E00XGC a valid ICD-10-PCS code for 2027?

Yes. 3E00XGC is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E00XGC?

The CMS GEMs map 3E00XGC to ICD-9-CM 85.92 (Injection of therapeutic agent into breast), 99.27 (Iontophoresis) and 99.86 (Non-invasive placement of bone growth stimulator).